For 30 peaceful years, Future Foundation kept at bay threat of Junko Enoshima's legacy. Unfortunately, they're no more. The world has fallen into chaos once again thanks to the Heralds of Despair, her successors. The Eternal Killing Game reminded you how futile fighting is. Their reach knows no limit, the end of everything was imminent... But the game ended. The students escaped. You saw hope again after almost two years of disaster and decided to fight back.

During your desperate struggle, you met them, the Anti-Herald Initiative. They have what it takes to end this war once and for all.

Will you join them?